All in

After years of playing safe it was time step up our game. 

We planned our next move, aware this wasn't a strategy game. Ultimately made the decision without knowing the rules of the game. 

Evidence based medicine has limits and so have I.

Desperate for relief we decided to go forward with plasmapheresis. Therapeutic plasma exchange can be used to remove autoantibodies or immune complexes circulating in the blood, attacking certain parts of body and causing symptoms. Plasmapheresis for seronegative whatever this is I have, definitely was an unconventional therapy approach. Credit to my doctor for agreeing on and reasoning this experimental treatment. 

After an exhausting week in hospital, I was discharged home. Relieved and hopeful. A week after plasma exchange my breathing started improving a bit, my fevers became less frequent, joint pain settled and most of all I had more energy.
Maybe numbers weren't doing it justice, but plasmapheresis really had a noticeable effect.

The effect of the plasma exchange started to wear off after about 6 weeks and we were left with the same set of cards. We went all in anyway.
I felt surprisingly anxious switching to a different antibody treatment. Considering our previous success rate, probably not that surprising after all.

It’s been a month since starting Dupilumab.
Patiently waiting, willing to give it a fair chance. 

Knowing we have an ace up our sleeves certainly would put my mind at ease.